An update on cancer- and chemotherapy-related cognitive dysfunction: current status. Review uri icon

Overview

abstract

  • The purpose of this review is to summarize the current literature on the effects of cancer treatment-related cognitive difficulties, with a focus on the effects of chemotherapy. Numerous patients have cognitive difficulties during and after cancer treatments and, for some, these effects last years after treatment. We do not yet fully understand which factors increase susceptibility to cognitive difficulties during treatment and which cause persistent problems. We review possible contributors, including genetic and biological factors. Mostly we focus is on cognitive effects of adjuvant chemotherapy for breast cancer; however, cognitive effects of chemotherapy on the elderly and brain tumor patients are also discussed.

publication date

  • June 1, 2011

Research

keywords

  • Antineoplastic Agents
  • Cognition Disorders
  • Neoplasms

Identity

PubMed Central ID

  • PMC3120018

Scopus Document Identifier

  • 79956216585

Digital Object Identifier (DOI)

  • 10.1053/j.seminoncol.2011.03.014

PubMed ID

  • 21600374

Additional Document Info

volume

  • 38

issue

  • 3