Primary malignant bone tumors--recent developments. Review uri icon

Overview

abstract

  • Primary malignant bone tumors are rare sarcomas with an estimated frequency of about 2900 new cases per year; they constitute less than 0.2% of all cancers diagnosed in the United States. The diagnosis and management of these neoplasms require a team approach, which includes orthopaedic surgeons, radiologists, pathologists, and oncologists. With this approach and current treatment modalities, the 5-year survival for the most common malignant bone tumors, osteosarcoma and Ewing sarcoma, are 70% and 60%, respectively. This review will summarize recent developments and advances in molecular pathogenesis of the more common primary malignant bone neoplasms.

publication date

  • February 1, 2011

Research

keywords

  • Bone Neoplasms
  • Chondrosarcoma
  • Chordoma
  • Osteosarcoma
  • Sarcoma, Ewing

Identity

Scopus Document Identifier

  • 79955490402

PubMed ID

  • 21675380

Additional Document Info

volume

  • 28

issue

  • 1