Prolonged preservation of cadaver heart with Belzer UW solution: 24-hour storage system for asphyxiated canine hearts. Academic Article uri icon

Overview

abstract

  • The efficacy of Belzer UW solution was compared to Collins' solution in the preservation of asphyxiated cadaver hearts in a canine model. Donor hearts were stored for 24 h: 2 h of in situ hypothermic (15 degrees C) coronary perfusion plus 22 h of simple immersion in ice-cold solution. Verapamil, propranolol and prostacyclin were used for myocytoprotection in both groups. After orthotopic transplantation, all animals were weaned off bypass without inotropic support. After 1 h, however, the cardiac output was significantly higher in the Belzer UW solution group (128 +/- 28 vs. 67 +/- 13 ml/kg/min, p less than 0.01).

publication date

  • January 1, 1990

Research

keywords

  • Asphyxia
  • Heart
  • Heart Transplantation
  • Organ Preservation
  • Organ Preservation Solutions
  • Solutions

Identity

Scopus Document Identifier

  • 0025155269

PubMed ID

  • 2265654

Additional Document Info

volume

  • 22

issue

  • 4