Stepwise connectivity of the modal cortex reveals the multimodal organization of the human brain. Academic Article uri icon

Overview

abstract

  • How human beings integrate information from external sources and internal cognition to produce a coherent experience is still not well understood. During the past decades, anatomical, neurophysiological and neuroimaging research in multimodal integration have stood out in the effort to understand the perceptual binding properties of the brain. Areas in the human lateral occipitotemporal, prefrontal, and posterior parietal cortices have been associated with sensory multimodal processing. Even though this, rather patchy, organization of brain regions gives us a glimpse of the perceptual convergence, the articulation of the flow of information from modality-related to the more parallel cognitive processing systems remains elusive. Using a method called stepwise functional connectivity analysis, the present study analyzes the functional connectome and transitions from primary sensory cortices to higher-order brain systems. We identify the large-scale multimodal integration network and essential connectivity axes for perceptual integration in the human brain.

publication date

  • August 1, 2012

Research

keywords

  • Brain Mapping
  • Cerebral Cortex
  • Mental Processes
  • Models, Neurological
  • Neural Pathways
  • Sensation

Identity

PubMed Central ID

  • PMC3483645

Scopus Document Identifier

  • 84863724428

Digital Object Identifier (DOI)

  • 10.1523/JNEUROSCI.0759-12.2012

PubMed ID

  • 22855814

Additional Document Info

volume

  • 32

issue

  • 31