Genomic dysregulation in gastric tumors. Review uri icon

Overview

abstract

  • Gastric cancer is among the most common human malignancies and the second leading cause of cancer-related death. The different epidemiologic and histopathology of subtypes of gastric cancer are associated with different genomic patterns. Data suggests that gene expression patterns of proximal, distal gastric cancers-intestinal type, and diffuse/signet cell are well separated. This review summarizes the genetic and epigenetic changes thought to drive gastric cancer and the emerging paradigm of gastric cancer as three unique disease subtypes.

publication date

  • October 5, 2012

Research

keywords

  • Chromosome Aberrations
  • Stomach Neoplasms

Identity

Scopus Document Identifier

  • 84873409351

Digital Object Identifier (DOI)

  • 10.1002/jso.23263

PubMed ID

  • 23042588

Additional Document Info

volume

  • 107

issue

  • 3