Pilot study of feasibility and dosimetric comparison of prone versus supine breast radiotherapy. Academic Article uri icon

Overview

abstract

  • PURPOSE: The aim of this study was to demonstrate feasibility and analyze dosimetric differences in prone and supine position breast cancer radiotherapy in women with large or pendulous breast. METHODS: Ten post-lumpectomy breast cancer patients underwent supine and prone computed tomography-based treatment plan. On each data set, the whole breast, the ipsilateral lung and the heart were outlined. Multisegment tangential-fields plans were generated for each position. Target coverage, homogeneity, overdosage outside breast and organ at risk sparing were analyzed and compared for supine and prone position. RESULTS: Coverage and dose homogeneity of the PTV measured by D 90 and V(95)% were similar for both plans although breast maximum dose was higher in the supine plan (p = 0.017). Prone position reduced the percentage of ipsilateral lung receiving 20 Gy (V(20Gy)) from 26.5 to 2.9 % (p = 0.007), medium lung dose, as well as the percentage of the heart receiving 35 Gy heart (V(35Gy)) from 3.4 to 1.2 % (p = 0.038). Overdosage of areas outside breast PTV was also consistently reduced with prone position (p = 0.012). In addition, average number of segments and monitor units needed was reduced in prone position. CONCLUSIONS: Prone position in large breast women appears to favor normal tissue sparing in breast radiotherapy as compared to supine position, without diminishing the target coverage.

publication date

  • November 10, 2012

Research

keywords

  • Adenocarcinoma
  • Breast Neoplasms
  • Carcinoma, Ductal, Breast
  • Radiotherapy Planning, Computer-Assisted
  • Radiotherapy, Intensity-Modulated

Identity

Scopus Document Identifier

  • 84878743486

Digital Object Identifier (DOI)

  • 10.1007/s12094-012-0950-8

PubMed ID

  • 23143949

Additional Document Info

volume

  • 15

issue

  • 6