A popular engagement at the ends. Article uri icon

Overview

abstract

  • Three recent studies converged on a specific protein-protein interface between TPP1 and telomerase as being crucial for the regulation of both telomerase recruitment and processivity in mammalian cells. An equivalent interaction appears to exist in budding yeast, making this a nearly universal means of telomerase regulation.

publication date

  • January 1, 2013

Research

keywords

  • Schizosaccharomyces pombe Proteins
  • Telomerase
  • Telomere-Binding Proteins

Identity

PubMed Central ID

  • PMC5560596

Scopus Document Identifier

  • 84872040417

Digital Object Identifier (DOI)

  • 10.1038/nsmb.2483

PubMed ID

  • 23288360

Additional Document Info

volume

  • 20

issue

  • 1