IncobotulinumtoxinA in clinical literature. Review uri icon

Overview

abstract

  • IncobotulinumtoxinA is the third neurotoxin type A to be approved for aesthetic use in the United States. Because incobotulinumtoxinA has been in use in Europe for some time, the clinical literature is fairly replete with references to its properties and characteristics, as well as its safety and efficacy. In North America, 2 pivotal trials, referred to as GL-1 and GL-2, investigated the safety and efficacy of incobotulinumtoxinA in the glabellar region; both are currently in press with another journal. Other published studies of incobotulinumtoxinA are also described in depth in this article, including reports on aesthetic indications, diffusion, therapeutic indications, and studies pertaining to the preclinical and clinical pharmacology of incobotulinumtoxinA. Topics addressed include potency variability, mean concentration, stability and dissociation, and endopeptide immunoassay.

publication date

  • March 1, 2013

Research

keywords

  • Botulinum Toxins, Type A
  • Face
  • Neurotransmitter Agents
  • Rejuvenation

Identity

Scopus Document Identifier

  • 84882982343

Digital Object Identifier (DOI)

  • 10.1177/1090820X12474635

PubMed ID

  • 23515196

Additional Document Info

volume

  • 33

issue

  • 1 Suppl