Advances in molecular and clinical subtyping of breast cancer and their implications for therapy. Review uri icon

Overview

abstract

  • The identification of the intrinsic molecular subtypes of breast cancer has enhanced our understanding of tumor biology, informing therapeutic targets, and clinical trial design. This article reviews the intrinsic classification system and the clinically defined subtypes of breast cancer. We review the molecular drivers of each subtype and discuss implications for prognosis, clinical management, and future directions.

publication date

  • July 27, 2013

Research

keywords

  • Breast Neoplasms

Identity

Scopus Document Identifier

  • 84883552212

Digital Object Identifier (DOI)

  • 10.1016/j.soc.2013.06.006

PubMed ID

  • 24012401

Additional Document Info

volume

  • 22

issue

  • 4