From molecular understanding to clinical advances. uri icon

Overview

abstract

  • Big data and computational biology brought to the forefront a number of potential actionable mutations and drug targets in clear cell renal cell carcinoma in 2013. As we continue to unravel the molecular underpinnings of tumorigenesis and progression, the clinical benefits will eventually be reaped.

publication date

  • December 24, 2013

Research

keywords

  • Carcinoma, Renal Cell
  • Hypoxia-Inducible Factor 1
  • Kidney Neoplasms
  • Receptors, CXCR4
  • Transcription Factors
  • Von Hippel-Lindau Tumor Suppressor Protein

Identity

Scopus Document Identifier

  • 84908128843

Digital Object Identifier (DOI)

  • 10.1038/nrurol.2013.307

PubMed ID

  • 24366347

Additional Document Info

volume

  • 11

issue

  • 2