Utility of cell salvage in women undergoing abdominal myomectomy. Academic Article uri icon

Overview

abstract

  • OBJECTIVE: We examined the use and cost of autologous blood cell salvage in women who undergo abdominal myomectomy. STUDY DESIGN: Patients who underwent abdominal myomectomy from 2007-2011 were identified. Use of the cell salvage system and reinfusion of autologous blood in women who had the system set-up were analyzed. Cost was examined by directly reported data. RESULTS: We identified 607 patients who underwent abdominal myomectomy. Four hundred twenty-five women (70%) had the set-up of the cell salvage system. Cell-salvaged blood was processed and reinfused into 85 of these subjects (20%). In a multivariable model, performance of myomectomy by a gynecologic-specific surgeon (odds ratio [OR], 2.14; 95% confidence interval [CI], 1.28-3.59), >5 myomas (OR, 2.49; 95% CI, 1.27-4.89), and larger uterine size statistically were associated significantly with cell-salvage device set-up. Conversely, having a reproductive-endocrinology-infertility specialist as the surgeon was associated with a significant reduction in cell-salvage system set-up (OR, 0.37; 95% CI, 0.21-0.66). For the women who had cell-salvage system set-up, uterine size of >15-19 weeks of gestation (OR, 3.22; 95% CI, 1.56-8.95) or ≥20 weeks of gestation (OR, 4.62; 95% CI, 1.45-14.73), operating time of >120 minutes (OR, 3.98; 95% CI, 1.70-9.29), and intraoperative blood loss of >1000 mL (OR, 26.31; 95% CI, 10.49-65.99) were associated significantly with a higher incidence of reinfusion of cell-salvaged blood. CONCLUSION: The routine use of cell salvage in women who undergo abdominal myomectomy does not appear to be warranted. Cell-salvage set-up appears to be cost-effective only when reinfused, but clinical characteristics cannot predict accurately which women will require reinfusion of cell-salvaged blood.

authors

  • Son, Moeun
  • Evanko, John C
  • Mongero, Linda B
  • Lewin, Sharyn N
  • Lu, Yu-Shiang
  • Herzog, Thomas J
  • Kim, Jin Hee
  • Wright, Jason D

publication date

  • February 21, 2014

Research

keywords

  • Blood Transfusion, Autologous
  • Leiomyoma
  • Operative Blood Salvage
  • Uterine Myomectomy
  • Uterine Neoplasms

Identity

Scopus Document Identifier

  • 84903398208

Digital Object Identifier (DOI)

  • 10.1016/j.ajog.2014.02.020

PubMed ID

  • 24565686

Additional Document Info

volume

  • 211

issue

  • 1