Granulocyte colony-stimulating factor: preclinical and clinical studies. Review uri icon

Overview

abstract

  • The production of neutrophil granulocytes is a complex and dynamic process during which a small number of self-renewing stem cells give rise to lineage-specific progenitors. One hematopoietic glycoprotein that appears to specifically control the survival, cycle activation, proliferation and terminal maturation of this myeloid lineage is granulocyte colony-stimulating factor (G-CSF). Some topics discussed are its molecular characterization, biochemical purification, sources, and effects of administration.

publication date

  • September 1, 1989

Research

keywords

  • Agranulocytosis
  • Bone Marrow Diseases
  • Colony-Stimulating Factors
  • Neutropenia

Identity

Scopus Document Identifier

  • 0024406448

PubMed ID

  • 2483722

Additional Document Info

volume

  • 3

issue

  • 3