Genetic diversity and population structure of Plasmodium vivax isolates from Sudan, Madagascar, French Guiana and Armenia. Academic Article uri icon

Overview

abstract

  • Polymorphic genetic markers and especially microsatellite analysis can be used to investigate multiple aspects of the biology of Plasmodium species. In the current study, we characterized 7 polymorphic microsatellites in a total of 281 Plasmodium vivax isolates to determine the genetic diversity and population structure of P. vivax populations from Sudan, Madagascar, French Guiana, and Armenia. All four parasite populations were highly polymorphic with 3-32 alleles per locus. Mean genetic diversity values was 0.83, 0.79, 0.78 and 0.67 for Madagascar, French Guiana, Sudan, and Armenia, respectively. Significant genetic differentiation between all four populations was observed.

publication date

  • August 4, 2014

Research

keywords

  • Genetic Variation
  • Malaria, Vivax
  • Plasmodium vivax

Identity

Scopus Document Identifier

  • 84907378379

Digital Object Identifier (DOI)

  • 10.1016/j.meegid.2014.07.029

PubMed ID

  • 25102032

Additional Document Info

volume

  • 27