Identification and characterization of linezolid-resistant cfr-positive Staphylococcus aureus USA300 isolates from a New York City medical center. Academic Article uri icon

Overview

abstract

  • The cfr gene was identified in three linezolid-resistant USA300 methicillin-resistant Staphylococcus aureus (MRSA) isolates collected over a 3-day period at a New York City medical center in 2011 as part of a routine surveillance program. Each isolate possessed a plasmid containing a pSCFS3-like cfr gene environment. Transformation of the cfr-bearing plasmids into the S. aureus ATCC 29213 background recapitulated the expected Cfr antibiogram, including resistance to linezolid, tiamulin, clindamycin, and florfenicol and susceptibility to tedizolid.

publication date

  • August 18, 2014

Research

keywords

  • Acetamides
  • Anti-Bacterial Agents
  • Bacterial Proteins
  • Methicillin-Resistant Staphylococcus aureus
  • Oxazolidinones

Identity

PubMed Central ID

  • PMC4249436

Scopus Document Identifier

  • 84908596733

Digital Object Identifier (DOI)

  • 10.1128/AAC.03380-14

PubMed ID

  • 25136008

Additional Document Info

volume

  • 58

issue

  • 11