In vivo protection by broadly neutralizing HIV antibodies. Article uri icon

Overview

abstract

  • Passive immunization studies, including a recent one by Pegu et al., have repeatedly shown that HIV-specific broadly neutralizing antibodies (bnAbs) protect rhesus macaques from HIV acquisition. In vitro neutralization potency and in vivo protection correlate very strongly, supporting the quest for an HIV vaccine that induces potent bnAbs.

publication date

  • August 26, 2014

Research

keywords

  • AIDS Vaccines
  • Antibodies, Neutralizing
  • HIV Antibodies
  • HIV Infections
  • HIV-1

Identity

Scopus Document Identifier

  • 84908477298

Digital Object Identifier (DOI)

  • 10.1016/j.tim.2014.08.006

PubMed ID

  • 25169020

Additional Document Info

volume

  • 22

issue

  • 10