Outcome of microsurgical testicular sperm extraction in familial idiopathic nonobstructive azoospermia. Academic Article uri icon

Overview

abstract

  • The aim of the study was to evaluate the sperm retrieval rate by microsurgical testicular sperm extraction (TESE) in familial idiopathic nonobstructive azoospermia (NOA). One hundred and nineteen patients with idiopathic NOA who underwent microsurgical TESE over the past 5 years were included. Patients were then divided into two groups; Group 'A' with familial idiopathic NOA (11 families with two brothers in each family, 22 patients) and Group 'B' with nonfamilial idiopathic NOA (97 patients). Clinical data as well as data of microsurgical TESE were recorded. In Group 'A', the sperm retrieval rate was 9.1% (2/22 patients) compared to 45.4% in Group 'B' (44/97 patients) (P ≤ 0.05). The two patients in Group 'A' with successful sperm retrieval belonged to one family. The histopathological diagnosis was the same in the brothers in each family. It can be concluded that the testicular sperm retrieval rate in familial idiopathic NOA is significantly lower than in nonfamilial idiopathic NOA.

publication date

  • November 18, 2014

Research

keywords

  • Azoospermia
  • Microsurgery
  • Sperm Retrieval
  • Spermatozoa
  • Testis

Identity

Scopus Document Identifier

  • 84973124407

Digital Object Identifier (DOI)

  • 10.1111/and.12378

PubMed ID

  • 25404040

Additional Document Info

volume

  • 47

issue

  • 9