Society of Gynecologic Oncology recommendations for the prevention of ovarian cancer. Review uri icon

Overview

abstract

  • Mortality from ovarian cancer may be dramatically reduced with the implementation of attainable prevention strategies. The new understanding of the cells of origin and the molecular etiology of ovarian cancer warrants a strong recommendation to the public and health care providers. This document discusses potential prevention strategies, which include 1) oral contraceptive use, 2) tubal sterilization, 3) risk-reducing salpingo-oophorectomy in women at high hereditary risk of breast and ovarian cancer, 4) genetic counseling and testing for women with ovarian cancer and other high-risk families, and 5) salpingectomy after childbearing is complete (at the time of elective pelvic surgeries, at the time of hysterectomy, and as an alternative to tubal ligation). The Society of Gynecologic Oncology has determined that recent scientific breakthroughs warrant a new summary of the progress toward the prevention of ovarian cancer. This review is intended to emphasize the importance of the fallopian tubes as a potential source of high-grade serous cancer in women with and without known genetic mutations in addition to the use of oral contraceptive pills to reduce the risk of ovarian cancer.

publication date

  • March 27, 2015

Research

keywords

  • Ovarian Neoplasms

Identity

Scopus Document Identifier

  • 84931068694

Digital Object Identifier (DOI)

  • 10.1002/cncr.29321

PubMed ID

  • 25820366

Additional Document Info

volume

  • 121

issue

  • 13