Parathyroid Localization and Preservation during Transcervical Resection of Substernal Thyroid Glands. Academic Article uri icon

Overview

abstract

  • OBJECTIVE: The feasibility of parathyroid preservation during thyroidectomy has not been well documented for cases in which the thyroid gland extends into the mediastinum. STUDY DESIGN: Retrospective chart review. SETTING: Tertiary academic referral center. SUBJECTS AND METHODS: In this retrospective cohort study, 70 consecutive patients who had substernal thyroid glands treated with a transcervical thyroidectomy between 1993 and 2013 were compared with 286 thyroidectomies that did not entail substernal extension within that same time period. All localized parathyroid glands were confirmed histologically. RESULTS: Of 160 possible parathyroid glands in the substernal cases, 119 (74%) were histologically confirmed intraoperatively (67 superior and 52 inferior). In nonsubsternal cases, 725 (89%) were histologically confirmed (372 superior and 353 inferior). There was a statistically significant difference between the substernal and nonsubsternal cases in the total number of glands found (P < .0001) and the number of superior and inferior glands that were identified (P = .009 and < 0.0001). CONCLUSIONS: Even when the thyroid gland extends into the mediastinum, it is often possible, although with reduced efficiency, to identify and preserve the parathyroid glands.

publication date

  • April 6, 2015

Research

keywords

  • Organ Sparing Treatments
  • Parathyroid Glands
  • Thyroid Gland
  • Thyroidectomy

Identity

Scopus Document Identifier

  • 84930407029

Digital Object Identifier (DOI)

  • 10.1177/0194599815578105

PubMed ID

  • 25847147

Additional Document Info

volume

  • 152

issue

  • 6