Diuretic 18F-Fluorodeoxyglucose PET/Computed Tomography in Evaluation of Genitourinary Malignancies.
Review
Overview
abstract
The interpretation of fluorodeoxyglucose (FDG) PET/computed tomography (CT) is often challenging for pelvic pathologies because of the physiologic bowel and urinary tract activity. Intense radiotracer activity in urinary tract interferes in image interpretation and leads to false-negative results in diagnosis and detection of local recurrence and regional lymph node metastases. It is imperative to minimize unnecessary urinary bladder activity to improve the diagnostic yield of PET/CT. All the techniques described in the literature have their pros and cons. This article discusses FDG PET/CT in evaluation of urinary bladder cancer, cervical cancer, and ovarian cancer.