Hairy cell leukemia: Past, present and future. Review uri icon

Overview

abstract

  • This brief review highlights the sequence of therapeutic milestones and advances in our understanding of the biology of hairy cell leukemia (HCL) with a focus on recent molecular findings and how these may be applied to improve disease outcomes in the future. Targeted therapy is discussed in the context of the recently identified BRAF mutation and other genetic findings.

publication date

  • October 21, 2015

Research

keywords

  • Antineoplastic Agents
  • B-Lymphocytes
  • Indoles
  • Leukemia, Hairy Cell
  • Proto-Oncogene Proteins B-raf
  • Sulfonamides

Identity

PubMed Central ID

  • PMC5008915

Scopus Document Identifier

  • 84952314340

Digital Object Identifier (DOI)

  • 10.1016/j.beha.2015.10.015

PubMed ID

  • 26614906

Additional Document Info

volume

  • 28

issue

  • 4