Rapidly Progressive Transthyretin-Mediated Amyloidosis in a Domino Liver Transplant Recipient of a Ser23Asn Donor. uri icon

Overview

abstract

  • Domino liver transplantation, in which the liver of a patient with transthyretin-mediated amyloidosis is transplanted into another patient, has been an established procedure performed at several centers across the world. The risk of developing systemic amyloidosis in transthyretin-mediated amyloidosis liver transplant recipients is a topic of ongoing investigation. We report a case of rapidly progressive transthyretin amyloidosis in a patient who received a liver from a donor with a rare Ser23Asn mutation. We advise exercising caution when considering domino liver transplantation in patients with this particular mutation.

publication date

  • March 1, 2016

Research

keywords

  • Amyloid Neuropathies, Familial
  • Liver Transplantation
  • Mutation
  • Prealbumin

Identity

Scopus Document Identifier

  • 84959931614

Digital Object Identifier (DOI)

  • 10.1097/CND.0000000000000110

PubMed ID

  • 26905915

Additional Document Info

volume

  • 17

issue

  • 3