Radioresistance induced by oncogenic transformation. Academic Article uri icon

Overview

abstract

  • Rat embryo cells at various stages of oncogenic transformation are obtained by a combination of X irradiation and transfection with the ras and the myc oncogenes. Transfection with either the ras or the myc oncogenes can lead to increased radioresistance, relative to the parental cells. X-ray-transformed clones of the transfected cells do not show additional alteration in radioresponse. Incorporation of the two oncogenes appears to lead to a higher degree of radioresistance.

publication date

  • November 1, 1989

Research

keywords

  • Cell Transformation, Neoplastic
  • Oncogenes
  • Radiation Tolerance
  • Transfection

Identity

Scopus Document Identifier

  • 0024363796

PubMed ID

  • 2694214

Additional Document Info

volume

  • 120

issue

  • 2