AOM/DSS Model of Colitis-Associated Cancer. Academic Article uri icon

Overview

abstract

  • Our understanding of colitis-associated carcinoma (CAC) has benefited substantially from mouse models that faithfully recapitulate human CAC. Chemical models, in particular, have enabled fast and efficient analysis of genetic and environmental modulators of CAC without the added requirement of time-intensive genetic crossings. Here we describe the Azoxymethane (AOM)/Dextran Sodium Sulfate (DSS) mouse model of inflammatory colorectal cancer.

publication date

  • January 1, 2016

Research

keywords

  • Azoxymethane
  • Colitis
  • Colorectal Neoplasms
  • Dextran Sulfate
  • Disease Models, Animal

Identity

PubMed Central ID

  • PMC5035391

Scopus Document Identifier

  • 84990041911

Digital Object Identifier (DOI)

  • 10.1007/978-1-4939-3603-8_26

PubMed ID

  • 27246042

Additional Document Info

volume

  • 1422