Alternative core development around the tetracyclic indole class of HCV NS5A inhibitors.
Academic Article
Overview
abstract
Herein, we describe our research efforts to develop unique cores in molecules which function as HCV nonstructural protein 5A (NS5A) inhibitors. In particular, various fused tetracyclic cores were identified which showed genotype and mutant activities comparable to the indole-based tetracyclic core.
