Local Inhibition of Macrophage and Smooth Muscle Cell Proliferation to Suppress Plaque Progression. Review uri icon

Overview

abstract

  • Atherosclerosis is a complex process responsible for a major burden of cardiovascular morbidity and mortality. Macrophages and smooth muscle cells (SMCs) are abundant within atherosclerotic plaques. This review discusses the role of macrophages and SMCs in plaque progression and provides an overview of nanoparticle-based approaches and other current methods for local targeting of atherosclerotic plaques.

publication date

  • September 1, 2016

Research

keywords

  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • Macrophages
  • Muscle, Smooth, Vascular
  • Plaque, Atherosclerotic

Identity

PubMed Central ID

  • PMC5098570

Scopus Document Identifier

  • 85020374622

PubMed ID

  • 27826367

Additional Document Info

volume

  • 12

issue

  • 3