Exploring the nexus of Alzheimer's disease and related dementias with cancer and cancer therapies: A convening of the Alzheimer's Association & Alzheimer's Drug Discovery Foundation. Review uri icon

Overview

abstract

  • Recent population studies suggest an intriguing inverse relationship between several types of cancer and neurodegenerative diseases, including Alzheimer's disease. Understanding the intersection of the underlying biology for these two distinct families of diseases with one another may offer novel approaches to identify new therapeutic approaches and possible opportunities to repurpose existing drug candidates. The Alzheimer's Association and the Alzheimer's Drug Discovery Foundation convened a one-day workshop to delve into this discussion. Workshop participants outlined research focus areas, potential collaborations, and partnerships for future action.

authors

  • Snyder, Heather M
  • Ahles, Tim
  • Calderwood, Stuart
  • Carrillo, Maria C
  • Chen, Honglei
  • Chang, Chung-Chou H
  • Craft, Suzanne
  • De Jager, Philip
  • Driver, Jane A
  • Fillit, Howard
  • Knopman, David
  • Lotze, Michael
  • Tierney, Mary C
  • Petanceska, Suzana
  • Saykin, Andrew
  • Seshadri, Sudha
  • Shineman, Diana
  • Ganguli, Mary

publication date

  • December 18, 2016

Research

keywords

  • Alzheimer Disease
  • Antineoplastic Agents
  • Dementia
  • Neoplasms

Identity

PubMed Central ID

  • PMC5548424

Scopus Document Identifier

  • 85009285148

Digital Object Identifier (DOI)

  • 10.1016/j.jalz.2016.11.002

PubMed ID

  • 27998721

Additional Document Info

volume

  • 13

issue

  • 3