Intraductal Carcinoma of the Prostate: A Risk for Rapid Recurrence. uri icon

Overview

abstract

  • Intraductal carcinoma of the prostate (IDC-P), recently defined by the World Health Organization in 2016, is a distinct histologic entity associated with an aggressive clinical course, including increased risk of biochemical recurrence, metastasis, and mortality. Differential diagnosis includes intraductal spread of urothelial carcinoma, prostatic ductal carcinoma, and high-grade prostatic intraepithelial neoplasia. BRCA mutations are associated with an increased risk of IDC-P. The presence of IDC-P on initial biopsy or radical prostatectomy should trigger aggressive treatment and should be considered a contraindication to active surveillance, regardless of tumor volume.

publication date

  • March 28, 2017

Research

keywords

  • Carcinoma, Ductal
  • Neoplasm Recurrence, Local
  • Prostatic Neoplasms

Identity

Scopus Document Identifier

  • 85018636078

Digital Object Identifier (DOI)

  • 10.1016/j.urology.2017.03.030

PubMed ID

  • 28363741

Additional Document Info

volume

  • 105