Acral angiokeratoma-like pseudolymphoma in a middle-aged woman. uri icon

Overview

abstract

  • Acral angiokeratoma-like pseudolymphoma is a rare type of pseudolymphoma presenting as dark-red papules on the hand or foot. We describe a 59-year-old woman who presented with an unusual unilateral, clustered aggregate of scaly violaceous papules on the toe with an indolent course. Skin biopsy showed a prominent vascular proliferation associated with a dermal infiltrate of monoclonally rearranged T-follicular helper phenotype T-cells, in keeping with CD4+ small/medium T-cell lymphoproliferative disorder (SMPTC-LPD). Based on the unique clinical morphology, distribution of the lesions and dermoscopic appearance, a clinicopathologic diagnosis of acral angiokeratoma-like pseudolymphoma was favored. This case demonstrates the importance of clinicopathological correlation in such diagnostically challenging patients who present with overlapping features on the spectrum of pseudolymphoma and cutaneous T-cell lymphoma.

publication date

  • July 24, 2017

Research

keywords

  • Angiokeratoma
  • Lymphoma, T-Cell, Cutaneous
  • Skin Neoplasms
  • T-Lymphocytes, Helper-Inducer

Identity

PubMed Central ID

  • PMC5053827

Scopus Document Identifier

  • 85029683222

Digital Object Identifier (DOI)

  • 10.1111/cup.12999

PubMed ID

  • 28675468

Additional Document Info

volume

  • 44

issue

  • 10