A Precious Diagnostic "Pearl": The Necklace Pattern in Germ Cell Tumors of the Testis. uri icon

Overview

abstract

  • Diffuse embryoma is a rare pattern of nonseminomatous germ cell tumor of the testis originally described in 1983. We report a case with this predominant pattern in an 18-year-old male with a painless palpable testicular mass. Although it is relatively common to see a diffuse embryoma pattern focally in mixed nonseminomatous germ cell tumors of the testis, it is rarely the predominant pattern and can represent a diagnostic pitfall on routine hematoxylin and eosin stain. We emphasize the importance of recognizing the individual components within the diffuse embryoma pattern, review the literature, and briefly discuss the ancillary immunohistochemical stains that may be utilized to help support the diagnosis.

publication date

  • September 1, 2017

Research

keywords

  • Neoplasms, Germ Cell and Embryonal
  • Testicular Neoplasms

Identity

Scopus Document Identifier

  • 85042137821

Digital Object Identifier (DOI)

  • 10.1177/1066896917729502

PubMed ID

  • 28862048

Additional Document Info

volume

  • 26

issue

  • 2