The genetic framework for development of nephrolithiasis. Review uri icon

Overview

abstract

  • Over 1%-15% of the population worldwide is affected by nephrolithiasis, which remains the most common and costly disease that urologists manage today. Identification of at-risk individuals remains a theoretical and technological challenge. The search for monogenic causes of stone disease has been largely unfruitful and a technological challenge; however, several candidate genes have been implicated in the development of nephrolithiasis. In this review, we will review current data on the genetic inheritance of stone disease, as well as investigate the evolving role of genetic analysis and counseling in the management of nephrolithiasis.

publication date

  • November 28, 2016

Identity

PubMed Central ID

  • PMC5730897

Scopus Document Identifier

  • 85027825337

Digital Object Identifier (DOI)

  • 10.1016/j.ajur.2016.11.003

PubMed ID

  • 29264202

Additional Document Info

volume

  • 4

issue

  • 1