Prognostic value of lymph node ratio in head and neck squamous cell carcinoma. Review uri icon

Overview

abstract

  • BACKGROUND: Lymph node ratio (LNR) is increasingly reported as a potential prognostic tool. The purpose of this review was to analyze the available literature on the prognostic significance of LNR in head and neck squamous cell carcinoma (HNSCC). METHODS: A PubMed internet search was performed and articles meeting selection criteria were reviewed. RESULTS: Twenty-eight studies were identified in the literature dealing with the prognostic value of LNR. The published results are variable with a range of cutoff values of LNR associated with prognosis (overall survival [OS] and/or disease-specific survival [DSS]) between 0.02 and 0.20, with an average of 0.09. CONCLUSION: The LNR is reported to be of value in assessing prognosis in the patients with HNSCC. Although it is easy to calculate and could be considered in the staging of these patients, the currently available evidence in the literature does not yet provide a solid base for implementation.

publication date

  • February 2, 2018

Research

keywords

  • Head and Neck Neoplasms
  • Squamous Cell Carcinoma of Head and Neck

Identity

Scopus Document Identifier

  • 85041325693

Digital Object Identifier (DOI)

  • 10.1002/hed.25080

PubMed ID

  • 29394461

Additional Document Info

volume

  • 40

issue

  • 5