Durable response in a woman with recurrent low-grade endometrioid endometrial cancer and a germline BRCA2 mutation treated with a PARP inhibitor. uri icon

Overview

abstract

  • A 42-year-old woman with a germline BRCA2 mutation and recurrent low-grade endometrioid endometrial adenocarcinoma experienced clinical and radiographic response to the poly (ADP ribose) polymerase (PARP) inhibitor, olaparib. Molecular and treatment factors are discussed.

publication date

  • June 22, 2018

Research

keywords

  • BRCA2 Protein
  • Carcinoma, Endometrioid
  • Endometrial Neoplasms
  • Germ-Line Mutation
  • Poly(ADP-ribose) Polymerase Inhibitors

Identity

Scopus Document Identifier

  • 85048865193

Digital Object Identifier (DOI)

  • 10.1016/j.ygyno.2018.05.028

PubMed ID

  • 29937315

Additional Document Info

volume

  • 150

issue

  • 2