Amniotic-Derived Treatments and Formulations. Review uri icon

Overview

abstract

  • In orthopedic sports medicine, amniotic-derived products have demonstrated promising preclinical and early clinical results for the treatment of tendon/ligament injuries, cartilage defects, and osteoarthritis. The amniotic membrane is a metabolically active tissue that has demonstrated anti-inflammatory, antimicrobial, antifibrotic, and epithelialization-promoting features that make it uniquely suited for several clinical applications. Although the existing clinical literature is limited, there are several ongoing clinical trials aiming to elucidate the specific applications and benefits of these products. This article reviews the current amniotic-derived treatment options and the existing literature on outcomes, complications, and safety profile of these products for use in sports medicine.

publication date

  • January 1, 2019

Research

keywords

  • Amnion
  • Cartilage Diseases
  • Osteoarthritis
  • Sports Medicine
  • Tendon Injuries

Identity

Scopus Document Identifier

  • 85056792911

Digital Object Identifier (DOI)

  • 10.1016/j.csm.2018.08.002

PubMed ID

  • 30466722

Additional Document Info

volume

  • 38

issue

  • 1