Diabetes and Metabolic Syndrome in Survivors of Childhood Cancer. Review uri icon

Overview

abstract

  • Endocrine complications, including diabetes and metabolic syndrome, are highly prevalent in childhood cancer survivors. These metabolic derangements may contribute to survivors' risk of excess cardiovascular morbidity and premature mortality. This review summarizes existing knowledge on risk of diabetes and metabolic syndrome among childhood cancer survivors, focusing specifically on known risk factors, potential mechanisms, and screening recommendations. Early diagnosis via standardized risk-based screening can improve long-term outcomes in this population. Additional work is needed to elucidate the mechanisms underlying these metabolic complications and to inform the design of risk-reducing interventions and optimize long-term cardiometabolic health among survivors of childhood cancer.

publication date

  • January 16, 2019

Research

keywords

  • Cancer Survivors
  • Diabetes Mellitus
  • Metabolic Syndrome
  • Neoplasms

Identity

PubMed Central ID

  • PMC6610586

Scopus Document Identifier

  • 85060212538

Digital Object Identifier (DOI)

  • 10.1159/000495698

PubMed ID

  • 30650414

Additional Document Info

volume

  • 91

issue

  • 2