The expanding use of matrix-assisted laser desorption/ionization-time of flight mass spectroscopy in the diagnosis of patients with mycotic diseases. Review uri icon

Overview

abstract

  • INTRODUCTION: Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) has emerged as a powerful new tool to identify human fungal pathogens and has radically altered the diagnostic mycology workflow at many medical centers around the world. Areas covered: While most experience is with the identification of yeasts, including species of Candida and Cryptococcus, there is ongoing work investigating the role of MALDI-TOF MS to detect molds, including species of Aspergillus, Fusarium, Scedosporium, and Mucormyctes as well as thermally dimorphic fungi. Expert commentary: In this paper, we review the current knowledge about this important new platform and examine how its expanding use may impact molecular diagnostics and patient care in the years ahead.

publication date

  • February 5, 2019

Research

keywords

  • Molecular Diagnostic Techniques
  • Mycoses
  • Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Identity

Scopus Document Identifier

  • 85063223698

Digital Object Identifier (DOI)

  • 10.1080/14737159.2019.1574572

PubMed ID

  • 30682890

Additional Document Info

volume

  • 19

issue

  • 3