Successful management of epithelial ingrowth after sequential intracameral 5-fluorouracil and Descemet-stripping automated endothelial keratoplasty. uri icon

Overview

abstract

  • To describe the successful treatment of epithelial ingrowth using combined surgical excision with intracameral adjuvant 5-fluorouracil (5-FU) followed by Descemet-stripping automated endothelial keratoplasty (DSAEK). A 71-year-old man presented with epithelial ingrowth after clear corneal phacoemulsification. He underwent surgical excision of the membrane together with pars plana vitrectomy, air fluid exchange, and intracameral 5-FU. This treatment resulted in corneal decompensation for which DSAEK was performed 6 months later. Despite interface haze, the postoperative corrected distance visual acuity returned to 20/40 three months after DSAEK. There was no clinical evidence of recurrence of the epithelial ingrowth 9 months after the surgical removal. Intracameral 5-FU can be used in conjunction with surgical excision and subsequent DSAEK to successfully treat epithelial ingrowth.

publication date

  • March 8, 2019

Research

keywords

  • Anterior Chamber
  • Antimetabolites
  • Corneal Diseases
  • Descemet Stripping Endothelial Keratoplasty
  • Epithelium, Corneal
  • Fluorouracil

Identity

Scopus Document Identifier

  • 85062388761

Digital Object Identifier (DOI)

  • 10.1016/j.jcrs.2018.12.030

PubMed ID

  • 30853320

Additional Document Info

volume

  • 45

issue

  • 5