Diagnosis and Genotyping of Coxiella burnetii Endocarditis in a Patient with Prosthetic Pulmonary Valve Replacement Using Next-Generation Sequencing of Plasma Microbial Cell-Free DNA. Academic Article uri icon

Overview

abstract

  • Determining the causative etiology of culture-negative endocarditis can be challenging. We performed next-generation sequencing of plasma microbial cell-free DNA to facilitate rapid diagnosis and genotyping of Coxiella burnetii in a patient with culture-negative endocarditis of a prosthetic pulmonary valve, enabling early targeted treatment prior to valve replacement surgery.

publication date

  • June 1, 2019

Identity

PubMed Central ID

  • PMC6580995

Scopus Document Identifier

  • 85079571649

Digital Object Identifier (DOI)

  • 10.1093/ofid/ofz242

PubMed ID

  • 31249846

Additional Document Info

volume

  • 6

issue

  • 6