Improving Cardiac Resynchronisation Therapy. Review uri icon

Overview

abstract

  • CRT is a cornerstone of therapy for patients with heart failure and reduced ejection fraction. By restoring left ventricular (LV) electrical and mechanical synchrony, CRT can reduce mortality, improve LV function and reduce heart failure symptoms. Since its introduction, many advances have been made that have improved the delivery of and enhanced the response to CRT. Improving CRT outcomes begins with proper patient selection so CRT is delivered to all populations that could benefit from it, and limiting the implantation of CRT in those with a small chance of response. In addition, advancements in LV leads and delivery technologies coupled with multimodality imaging and electrical mapping have enabled operators to place coronary sinus leads in locations that will optimise electrical and mechanical synchrony. Finally, new pacing strategies using LV endocardial pacing or His bundle pacing have allowed for CRT delivery and improved response in patients with poor coronary sinus anatomy or lack of response to traditional CRT.

publication date

  • July 1, 2019

Identity

PubMed Central ID

  • PMC6702464

Scopus Document Identifier

  • 85071589649

Digital Object Identifier (DOI)

  • 10.15420/aer.2018.62.3

PubMed ID

  • 31463060

Additional Document Info

volume

  • 8

issue

  • 3