A comprehensive review of topical hemostatic agents: The good, the bad, and the novel. Review uri icon

Overview

abstract

  • Uncontrolled exsanguination remains the leading cause of death for trauma patients, many of whom die in the pre-hospital setting. Without expedient intervention, trauma-associated hemorrhage induces a host of systemic responses and acute coagulopathy of trauma. For this reason, health care providers and prehospital personal face the challenge of swift and effective hemorrhage control. The utilization of adjuncts to facilitate hemostasis was first recorded in 1886. Commercially available products haves since expanded to include topical hemostats, surgical sealants, and adhesives. The ideal product balances efficacy, with safety practicality and cost-effectiveness. This review of hemostasis provides a guide for successful implementation and simultaneously highlights future opportunities.

publication date

  • January 1, 2020

Research

keywords

  • Hemorrhage
  • Hemostatic Techniques
  • Hemostatics
  • Wounds and Injuries

Identity

Scopus Document Identifier

  • 85077107514

Digital Object Identifier (DOI)

  • 10.1097/TA.0000000000002508

PubMed ID

  • 31626024

Additional Document Info

volume

  • 88

issue

  • 1