Cardiac surgery in patients with Hemophilia:is it safe? Academic Article uri icon

Overview

abstract

  • BACKGROUND: The life expectancy of hemophiliacs is similar to that of the general population. As a result, the prevalence of age-related cardiovascular diseases has increased. We present our experience with hemophilia patients who underwent cardiac surgery in our Medical Center between 2004 and 2019. METHODS: All hemophilia patients who underwent cardiac surgery were identified, and their peri-operative data evaluated retrospectively. RESULTS: Ten patients were identified: six with hemophilia-A, one with hemophilia-B, and three with hemophilia-C (factor XI deficiency). Cardiac procedures included ten coronary artery bypass grafts and one aortic valve replacement. Hemophilia-A and B patients were treated with factor substitution, whereas patients with factor XI deficiency were treated with fresh frozen plasma. One patient died, and one patient suffered from non-active gastrointestinal bleeding. CONCLUSIONS: While major cardiac surgery can be performed safely on patients with hemophilia, a multidisciplinary team approach and strict postoperative monitoring are essential in order to achieve optimal results.

publication date

  • May 8, 2020

Research

keywords

  • Cardiac Surgical Procedures
  • Factor XI Deficiency
  • Heart Diseases
  • Hemophilia A
  • Hemophilia B

Identity

PubMed Central ID

  • PMC7206692

Scopus Document Identifier

  • 85084721277

Digital Object Identifier (DOI)

  • 10.1186/s13019-020-01123-0

PubMed ID

  • 32384896

Additional Document Info

volume

  • 15

issue

  • 1