A Novel Neurovascular Liaison Governing the Blood-Brain Barrier. uri icon

Overview

abstract

  • How circulating signals enter the median eminence to trigger homeostatic hypothalamic responses is not well understood. Jiang et al. describe a neural mechanism that increases endothelial fenestrations and enhances the hypothalamic response to the circulating hormone leptin, suggesting a novel way to regulate brain entry through vascular wall remodeling.

publication date

  • July 22, 2020

Research

keywords

  • Blood-Brain Barrier
  • Median Eminence

Identity

Scopus Document Identifier

  • 85088239896

Digital Object Identifier (DOI)

  • 10.1016/j.neuron.2020.06.024

PubMed ID

  • 32702343

Additional Document Info

volume

  • 107

issue

  • 2