Current Insights in Cutaneous Lupus Erythematosus Immunopathogenesis. Review uri icon

Overview

abstract

  • Cutaneous Lupus Erythematosus (CLE) is a clinically diverse group of autoimmune skin diseases with shared histological features of interface dermatitis and autoantibodies deposited at the dermal-epidermal junction. Various genetic and environmental triggers of CLE promote infiltration of T cells, B cells, neutrophils, antigen presenting cells, and NK cells into lesional skin. In this mini-review, we will discuss the clinical features of CLE, insights into CLE immunopathogenesis, and novel treatment approaches.

publication date

  • July 2, 2020

Research

keywords

  • Lupus Erythematosus, Cutaneous

Identity

PubMed Central ID

  • PMC7343764

Scopus Document Identifier

  • 85088450751

Digital Object Identifier (DOI)

  • 10.3389/fimmu.2020.01353

PubMed ID

  • 32714331

Additional Document Info

volume

  • 11