Nonsteroidal Antiinflammatory Drugs, Anticoagulation, and Upper Gastrointestinal Bleeding. Review uri icon

Overview

abstract

  • Advanced age, history of peptic ulcer disease, Helicobacter pylori, coadministration of nonsteroidal antiinflammatory drugs (NSAIDs), corticosteroids, anticoagulation, and antiplatelets are risk factors for gastrointestinal bleeding in the elderly. Awareness of these risks and appropriate use of NSAIDs, particularly in those needing antiplatelet or anticoagulant therapy, is critical to optimal management. Careful selection of elderly patients requiring antiplatelet, anticoagulation, or chronic NSAID therapy for cotherapy with proton pump inhibitors can significantly reduce morbidity and mortality from gastrointestinal bleeding.

publication date

  • November 2, 2020

Research

keywords

  • Anti-Inflammatory Agents, Non-Steroidal
  • Anticoagulants
  • Gastrointestinal Hemorrhage
  • Peptic Ulcer
  • Platelet Aggregation Inhibitors
  • Proton Pump Inhibitors

Identity

Scopus Document Identifier

  • 85094951779

Digital Object Identifier (DOI)

  • 10.1016/j.cger.2020.08.004

PubMed ID

  • 33213773

Additional Document Info

volume

  • 37

issue

  • 1