A dermatologic perspective on multisystem inflammatory syndrome in children. Review uri icon

Overview

abstract

  • As of May 2020, an emerging immune-mediated syndrome mainly affecting children has been detected primarily in Europe and the United States. The incidence of this syndrome appears to mirror the initial infectious assault, with a delay of several weeks. This syndrome has been termed "multisystem inflammatory syndrome in children" (MIS-C) and is observed in association with the coronavirus disease 2019 (COVID-19). The phenotypes of presentation include several characteristic features, including prolonged fever, skin eruption, neck stiffness, and gastrointestinal manifestations with pronounced abdominal pain. Shock and organ dysfunction on presentation are frequent but inconsistent, whereas respiratory distress is typically and notably absent. We have reviewed recently published data aiming to better understand MIS-C, with a focus on its mucocutaneous manifestations.

publication date

  • September 23, 2020

Research

keywords

  • COVID-19
  • Skin Diseases
  • Systemic Inflammatory Response Syndrome

Identity

PubMed Central ID

  • PMC7510439

Scopus Document Identifier

  • 85095935136

Digital Object Identifier (DOI)

  • 10.1002/jmv.26224

PubMed ID

  • 33972046

Additional Document Info

volume

  • 39

issue

  • 1