Robust diagnostic classification via Q-learning. Academic Article uri icon

Overview

abstract

  • Machine learning (ML) models have demonstrated the power of utilizing clinical instruments to provide tools for domain experts in gaining additional insights toward complex clinical diagnoses. In this context these tools desire two additional properties: interpretability, being able to audit and understand the decision function, and robustness, being able to assign the correct label in spite of missing or noisy inputs. This work formulates diagnostic classification as a decision-making process and utilizes Q-learning to build classifiers that meet the aforementioned desired criteria. As an exemplary task, we simulate the process of differentiating Autism Spectrum Disorder from Attention Deficit-Hyperactivity Disorder in verbal school aged children. This application highlights how reinforcement learning frameworks can be utilized to train more robust classifiers by jointly learning to maximize diagnostic accuracy while minimizing the amount of information required.

publication date

  • June 3, 2021

Research

keywords

  • Clinical Decision-Making
  • Decision Support Systems, Clinical
  • Machine Learning
  • Software

Identity

PubMed Central ID

  • PMC8175431

Scopus Document Identifier

  • 85107158275

Digital Object Identifier (DOI)

  • 10.1038/s41598-021-90000-4

PubMed ID

  • 34083579

Additional Document Info

volume

  • 11

issue

  • 1