Roles of calcitonin gene-related peptide in the skin, and other physiological and pathophysiological functions. Review uri icon

Overview

abstract

  • Skin immunity is regulated by many mediator molecules. One is the neuropeptide calcitonin gene-related peptide (CGRP). CGRP has roles in regulating the function of components of the immune system including T cells, B cells, dendritic cells (DCs), endothelial cells (ECs), and mast cells (MCs). Herein we discuss actions of CGRP in mediating inflammatory and vascular effects in various cutaneous models and disorders.

publication date

  • October 5, 2021

Identity

PubMed Central ID

  • PMC8551410

Digital Object Identifier (DOI)

  • 10.1016/j.bbih.2021.100361

PubMed ID

  • 34746878

Additional Document Info

volume

  • 18