Transcriptional analysis for tuberculosis in pregnant women from the PRACHITi study. Academic Article uri icon

Overview

abstract

  • A new tuberculosis diagnostic cartridge assay, which detects a 3-gene tuberculosis signature in whole blood, was not diagnostic in women with maternal tuberculosis disease in India (AUC = 0.72). In a cohort of pregnant women, we identified a novel gene set for TB diagnosis (AUC = 0.97) and one for TB progression (AUC = 0.96).

authors

  • Mathad, Jyoti S.
  • Queiroz, Artur T L
  • Bhosale, Ramesh
  • Alexander, Mallika
  • Naik, Shilpa
  • Kulkarni, Vandana
  • Andrade, Bruno B
  • Gupta, Amita

publication date

  • June 10, 2022

Research

keywords

  • Mycobacterium tuberculosis
  • Pregnancy Complications, Parasitic
  • Tuberculosis

Identity

Digital Object Identifier (DOI)

  • 10.1093/cid/ciac437

PubMed ID

  • 35686302