Luminal mapping reveals mesenteric predominance of colonic adenomas and adenocarcinomas. Academic Article uri icon

Overview

abstract

  • BACKGROUND: Previous studies have examined the relationship between colorectal tumor distribution and metastasis, but the tumor luminal location and associative risk factors promoting tumor growth remain unknown. METHODS: In this study, we mapped the luminal distribution of human colonic adenomas/adenocarcinomas and their association with various physiologic parameters. RESULTS: We identified a mesenteric predominance for colonic adenomas and adenocarcinomas. CONCLUSION: The findings of this study raise the possibility of novel mechanistic pathways in the development of adenomas and subsequent transformation into adenocarcinomas.

publication date

  • December 17, 2022

Research

keywords

  • Adenocarcinoma
  • Adenoma
  • Colonic Neoplasms
  • Colonic Polyps
  • Colorectal Neoplasms

Identity

Digital Object Identifier (DOI)

  • 10.1007/s12664-022-01285-w

PubMed ID

  • 36527596