Immunogenicity and Safety of Hepatitis B Virus (HBV) Vaccine With a Toll-Like Receptor 9 Agonist Adjuvant in HBV Vaccine-Naïve People With Human Immunodeficiency Virus. Academic Article uri icon

Overview

abstract

  • In this international, multicenter open-label study (ACTG A5379) of HepB-CpG vaccine in people with human immunodeficiency virus (HIV) without prior hepatitis B virus (HBV) vaccination, all 68 participants achieved HBV seroprotective titers after the 3-dose series in the primary analysis. No unexpected safety issues were observed.

authors

  • Marks, Kristen
  • Kang, Minhee
  • Umbleja, Triin
  • Avihingsanon, Anchalee
  • Sugandhavesa, Patcharaphan
  • Cox, Andrea L
  • Vigil, Karen
  • Perazzo, Hugo
  • Price, Jennifer C
  • Katsidzira, Leolin
  • Vernon, Christina
  • Alston-Smith, Beverly
  • Sherman, Kenneth E

publication date

  • August 14, 2023

Research

keywords

  • Hepatitis B
  • Hepatitis B virus

Identity

PubMed Central ID

  • PMC10681652

Scopus Document Identifier

  • 85164320262

Digital Object Identifier (DOI)

  • 10.1093/cid/ciad201

PubMed ID

  • 37017075

Additional Document Info

volume

  • 77

issue

  • 3