Immunogenicity and Safety of Hepatitis B vaccine with a Toll-like Receptor 9 Agonist Adjuvant (HEPLISAV-B) in HBV Vaccine-naive People with HIV. Academic Article uri icon

Overview

abstract

  • In this international, multicenter open-label study (ACTG A5379) of HepB-CpG vaccine in people with HIV without prior Hepatitis B Virus (HBV) vaccination, all 68 participants achieved HBV seroprotective titers after the 3-dose series in the primary analysis. No unexpected safety issues were observed.

authors

  • Marks, Kristen
  • Kang, Minhee
  • Umbleja, Triin
  • Avihingsanon, Anchalee
  • Sugandhavesa, Patcharaphan
  • Cox, Andrea L
  • Vigil, Karen
  • Perazzo, Hugo
  • Price, Jennifer C
  • Katsidzira, Leolin
  • Vernon, Christina
  • Alston-Smith, Beverly
  • Sherman, Kenneth E

publication date

  • April 5, 2023

Research

keywords

  • Hepatitis B
  • Hepatitis B virus

Identity

Digital Object Identifier (DOI)

  • 10.1093/cid/ciad201

PubMed ID

  • 37017075