T-SPOT.TB Reactivity in Southern African Children With and Without in Utero Human Immunodeficiency Virus Exposure. Academic Article

Overview

abstract

Infants who are human immunodeficiency virus (HIV)-exposed uninfected (iHEU) experience higher risk of infectious morbidity than infants HIV-unexposed uninfected (iHUU). We compared tuberculosis (TB) infection prevalence in 418 Bacillus Calmette-Guérin vaccinated sub-Saharan African iHEU and iHUU aged 9-18 months using T-SPOT.TB. Prevalence of TB infection was low and did not differ by HIV exposure status.

authors

Edlefsen, Paul T

Bhebhe, Lynnette

Motsumi, Kesego

Moyo, Sikhulile

Happel, Anna-Ursula

Mmasa, Nicholas

Gasper, Melanie A

Dubois, Melanie
Files, Megan A
Seshadri, Chetan
Duffy, Fergal
Aitchison, John
Netea, Mihai G
Jao, Jennifer
Cameron, Donald W
Gray, Clive M
Jaspan, Heather B
Powis, Kathleen M

publication date

October 13, 2023

published in

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America Journal

Research

keywords

HIV Infections
Latent Tuberculosis
Tuberculosis

Identity

PubMed Central ID

PMC10573724

Scopus Document Identifier

85174752398

Digital Object Identifier (DOI)

10.1093/cid/ciad356

PubMed ID

37293702

Additional Document Info

volume

77

issue

8